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Immediately after the "Anschluss" of Austria to the German Reich on March 12, 1938, the attacks against the Jewish population and their property began. On May 20, 1938, the "Nuremberg Laws" were introduced, which, regardless of the religious denomination, declared every human being a "full Jew" who had three Jewish grandparents. Occupational prohibitions and expropriations removed the affected persons from any basis of life. Legal harassment and immigration restrictions made it difficult to escape.
 
In June 1940, the IKG St. Pölten was dissolved, the remaining forced to relocate to Vienna. From February 1941 onwards, the deportations to the places of mass murder began. About 480 of the approximately 1000 Jewish and Jewish-defined people managed to escape, 22 people survived in so-called "protected mishaps" or as "submarines" in a hiding place.
 
422 men, women and children were murdered by the National Socialists. The fate of around 175 people is unknown.